Welcome

 Three-dimensional Electron Microscopy (3DEM) is becoming a key experimental method in Structural Biology. Recent advances in image acquisition and processing are yielding more structures determined at near-atomic resolution, as well as a wide range of macromolecular complexes and subcellular architectures determined at lower resolution.

 

map resolution statistics

A major goal of the EMDataResource team is to work with the 3DEM community to establish data validation methods that can be used in the structure determination process, define key indicators of a well-determined structure that should accompany every structure deposition, and implement appropriate validation procedures into a 3DEM validation pipeline. Following recommendations of the EM Validation Task Force (Henderson et al 2012), we are hosting new benchmark challenges here, with aim to stimulate further community discussions about validation procedures for 3DEM maps and map-derived models. Prior community-organized 3DEM challenge activities have included a Particle Picking Challenge (Zhu et al 2004),  CryoEM Modeling Challenge (Ludtke et al 2012),  CTF Challenge (Marabini et al 2015), Map and Model Cryo-EM Challenges (Lawson & Chiu 2018), and most recently the 2019 Model Metrics Challenge (Lawson et al in press).

News

Model Challenge: Symmetry Info Updated

The model challenge guide now holds corrected symmetry center info and BIOMT matrices for the proteasome, GroEL, and β-galactosidase targets. The changes are highlighted with red text and update date.

The previously posted symmetry info had used rounded values for the voxel sizes, yielding inprecise center coordinate and matrix element values. We apologize for the errors.

Model Challenge Submission Deadline Extended

The deadline for model challenge submissions is now changed to Friday June 17 (21:00 UTC).

We hope that this extension will be helpful to all of our challengers.

In addition, please be aware that indicated symmetry centers in the model challenge guide may not be exact. 
This issue was just raised by one participant—we are investigating and will send a further update about this soon.

Further note (4/28): symmetry issue has been resolved

Map Submission Deadline Extended (Again)

By popular request, we are extending the map challenge submission deadline to April 15, 2016 @ 21:00 UTC (5 PM US ET).  Click here to see the new deadline time in your location.

 

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EMDataResource Validation Challenges are supported by NIH National Institute of General Medical Sciences

Please send your challenge questions, comments and feedback to challenges@emdataresource.org

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