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EMDataBank Challenges

EMDataBank is hosting community-wide challenges to critically evaluate 3DEM methods that are coming into use, with the ultimate goal of developing recommendations for validation criteria associated with every 3DEM map deposited to the EM Data Bank (EMDB) and map-derived model deposited to Protein Data Bank (PDB). 

Committees comprised of respected 3DEM community members are charged to formulate the details for each challenge, including:

  • choosing challenge reference data
  • deciding what information participants will need to submit
  • deciding on criteria for validation and comparison of results
  • deciding on the timeline for challenge events
  • promoting worldwide participation
  • emphasizing the challenge as a collaborative and constructive activity
  • evaluating the results and producing a report

In 2015/2016 we are hosting two challenges that focus, respectively, on reconstruction and modelling at moderate to high resolution, with the goals of establishing benchmarks, comparing current practices, and evolving criteria for evaluation of results. Click here to view a mini-poster about the challenges that we have presented at recent meetings. In the future we plan to host additional challenges for reconstruction and interpretation at lower resolution.


EMDataResource Validation Challenges are supported by NIH National Institute of General Medical Sciences

Please send your challenge questions, comments and feedback to

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