JSB Special Issue: Coming Soon

More than half of the articles that will appear in the Journal of Structural Biology Special Issue on the 2016 CryoEM Map and Model Challenges are already accepted for publication and are either already online or will shortly appear there, as listed below.  Click here for access.

Revised Map Challenge Maps/Info Now Available by FTP

At the request of several Map Challenge participants we enabled submission of revised maps/info for 2016 Map Challenge entries in the period between mid-October 2017 and mid-January 2018. We offered this so that updated maps could be archived and referenced, e.g. as part of a contribution to the planned journal special issue.

Zenodo Community Created for Archiving Challenge Data and Results

To support the upcoming JSB Journal Special Issue, all of the map challenge files and associated metadata are now archived, with downloadable zip files divided up by benchmark. A PDF containing a compilation of web pages related to the map challenge is also included. To reference particular map entries submitted to the challenge, manuscripts can cite doi:10.5281/zenodo.1120379 along with emcd### identifiers.  UPDATE Jan 25, 2018: All model challenge data are now also archived at


Map Challenge

We are in the wrap-up phase of this challenge with all participants welcome to contribute articles to the planned JSB special issue.

Model Challenge

We are in the wrap-up phase of this challenge with all participants welcome to contribute articles to the planned JSB special issue.


 Three-dimensional Electron Microscopy (3DEM) is becoming a key experimental method in Structural Biology. Recent advances in image acquisition and processing are yielding more structures determined at near-atomic resolution, as well as a wide range of macromolecular complexes and subcellular architectures determined at lower resolution.


A major goal of the EMDataBank team is to work with the 3DEM community to establish data validation methods that can be used in the structure determination process, define key indicators of a well-determined structure that should accompany every structure deposition, and implement appropriate validation procedures into a 3DEM validation pipeline. Following recommendations of the EM Validation Task Force (Henderson et al 2012), we are hosting new benchmark challenges here, with aim to stimulate further community discussions about validation procedures for 3DEM maps and map-derived models. Prior community-organized 3DEM challenge activities have included a Particle Picking Challenge (Zhu et al 2004),  CryoEM Modeling Challenge (Ludtke et al 2012), and CTF Challenge (Marabini et al 2015).

EMDataBank Validation Challenges are supported by NIH National Institute of General Medical Sciences

Please send your challenge questions, comments and feedback to

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